On Wednesday, May 25, Sammy Infante had three hits and scored both FredNat runs, Yoander Rivero had both RBIs, but the FredNats lost the second game of the series 8-2 to the Salem Red Sox at Virginia Credit Union Stadium in Fredericksburg.
2018 first-round pick Mason Denaburg made his first appearance since August of 2019 after two surgeries and pitched 2+ innings while allowing four hits and four earned runs. Denaburg had a 1-2-3 1st inning but ran into trouble with two outs in the 2nd. He was replaced in the 3rd inning by Bryan Peña, who got out of a bases-loaded, nobody out jam unscathed. Denaburg threw 51 pitches and consistently had his fastball in the mid-90s.