The center is a part of George Mason University. According to the "Murals at Mason" Project Manager Yassmin Salem, planners chose the design to reflect the research activities at the science center. The mural shows animals native to the area and includes a Swallowtail Butterfly, a green Tree Frog, a Wood Duck, and a North American River Otter.
The Potomac Science Center focuses on environmental research and restoration of the Potomac River. The center also has Environmental Science and Policy, Geography, and Geo-Information Science programs.
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